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Literature summary for 2.7.12.2 extracted from

  • Benhamman, R.; Bai, F.; Drory, S.; Loubert-Hudon, A.; Ellis, B.; Matton, D.
    The Arabidopsis mitogen-activated protein kinase kinase kinase 20 (MKKK20) acts upstream of MKK3 and MPK18 in two separate signaling pathways involved in root microtubule functions (2017), Front. Plant Sci., 8, 1352 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana O80396
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Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein MKKK20 phosphorylates MKK3 Arabidopsis thaliana

Source Tissue

Source Tissue Comment Organism Textmining
additional information under normal conditions, kinases MKKK20, MKK3 and MPK20 are weakly expressed in all tissues Arabidopsis thaliana
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nectary
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Arabidopsis thaliana
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plant vascular cell
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Arabidopsis thaliana
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root tip
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Arabidopsis thaliana
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stipule
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Arabidopsis thaliana
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Synonyms

Synonyms Comment Organism
MKK3
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Arabidopsis thaliana

General Information

General Information Comment Organism
physiological function MKKK20 phosphorylates both mitogen-activated protein kinase kinase MKK3 and MPK18. When all three kinases are combined, no synergistic effect is observed on MPK18 phosphorylation. MKKK20 acts upstream of MPK18 and MKK3. MKKK20 and MKK3 mutants are sensitive to microtubule-disrupting drugs Arabidopsis thaliana